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Re: Vortioxetine (Brintellix-Trintellix) undopaminergic

Posted by SLS on November 20, 2021, at 12:52:19

In reply to Re: Vortioxetine (Brintellix-Trintellix), posted by undopaminergic on November 20, 2021, at 11:48:31

> Right. And they had chloral hydrate before barbiturates!

> > Chloral hydrate is not pleasant. I have taken it.

> You mean it lacks recreational potential in contrast to barbiturates and benzodiazepines?

> > No. It just feels almost like drinking alcohol. It felt yucky. Not pleasant for me.

> Many people enjoy drinking alcohol. Do you think some may find chloral hydrate likewise pleasant?

I don't know what percentage of people taking chloral hydrate, if any, find it likewise as pleasant as alcohol to dose themselves with. Do you happen to know? Did you find it pleasant when you took it? What was the amount and frequency of your chloral hydrate dosing to receive the maximal pleasant psychotropic effects?

> > I like zolpidem (Ambien). It is a potent sleep initiator with a short half-life - much like triazolam (Halcion), which is a benzodiazepine. The only major side effects for me were night-eating and some anterograde amnesia. Anterograde amnesia is more robust with triazolam than with zolpidem.

> I liked zolpidem as well. I've never tried triazolam, but I've used another short-acting benzodiazepine for sleep (initiation), namely midazolam (Dormicum), which appears to be available in the US only as injection (Versed?).

> > The issue you brought up is the classification of medications based upon nothing.

> Ah, I see. That ("based on nothing") was never my intention.

> > Arbitrary: Merriam-Webster
> >
> > 1. not planned or chosen for a particular reason An arbitrary number has been assigned to each district. : not based on reason or evidence I don't know why I chose that one; it was a completely arbitrary decision.
> >
> > 2. done without concern for what is fair or right Although arbitrary arrests are illegal, they continue to occur in many parts of the country.
> >
> I think I was thinking along the lines of definition 2. Not "fair", not "right", not "legitimate", not "kosher".

Can you provide me with a few examples of the arbitrary classification of drugs by the FDA?

> You seem to be disagreeing based on your definition of "arbitrary". You thought I meant something else than what I intended. Maybe "arbitrary" isn't the best choice of word -- what would *you* call it?


When was the last time you recognized that you had lost an argument?

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.




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