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Re: Vortioxetine (Brintellix-Trintellix)

Posted by SLS on November 18, 2021, at 2:45:06

In reply to Re: Vortioxetine (Brintellix-Trintellix) SLS, posted by undopaminergic on November 17, 2021, at 14:17:16

Hi.

> > My advice to you is that you try it vortioxetine if you have run out of options that have a low probability of working. You never know.

>
> You know that you never know how a particular drug is going to affect a particular individual. The other options at this time are clomipramine, asenapine, or even venlafaxine. However, the wheels are already in motion as far as vortioxetine is concerned. I'm lucky if I get to try any of them!

That's a great perspective. Prior to the 1950s, there were no true antidepressants. Amphetamines and cocaine had been used in the past. Chlorpromazine (Thorazine), the first antipsychotic, was first introduced in 1952 in France. The first antidepressant approved for depression was iproniazid, a MAOI, in 1958. Imipramine, the first tricyclic, was introduced in 1959. MAOIs and TCAs. That was it. SSRIs didn't emerge in the United States until the approval of fluoxetine in 1987.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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