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Re: Ritalin + an MAOi = Greater baseline D/NE? PeterMartin

Posted by linkadge on October 8, 2021, at 15:49:26

In reply to Re: Ritalin + an MAOi = Greater baseline D/NE?, posted by PeterMartin on October 6, 2021, at 14:10:53

Of course, I don't know for sure. Sometimes strange things happen when multiple pathways of neurotransmitter are inhibited. For example, in some animal models of DAT + COMT + MAO inhibition, dopamine levels are significantly reduced vs. normal animals. Some of this is likely the result of early life modifications in neurotransmission. Also, there are the autoreceptors which slow monoamine firing when synaptic levels become too elevated.

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