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Re: Is anyone now taking or has taken a TCA? Results? SLS

Posted by Mtom on September 21, 2021, at 12:46:42

In reply to Re: Is anyone now taking or has taken a TCA? Results? linkadge, posted by SLS on September 20, 2021, at 20:22:52

> I can't stress enough how critical it is stay within *your* individual dosage window for nortriptyline. Using blood tests to determine an effective dosage isn't always reliable. The recommended range of blood concentrations is 50-150 ng/mL. That's a pretty wide spread. At 150 mg/day of nortriptyline, my concentration was 153 ng/mL. My doctor moved it down to 100 mg/day. I discovered that I did not maintain a consistent antidepressant response until the dosage was dropped to 75 mg/day. 50 mg/day proved to be too low, as I began to relapse at that dosage. I might get a blood test for informational purposes.
> - Scott

That's interesting. I'm sure a read a paper recently that discussed how both too low a dose of TCA AND too high a dose were ineffective for depression. That would make things tricky with a lot of experimentation and time. I'm going to try to find it again...




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