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Re: Help..severe anger.... undopaminergic

Posted by SLS on September 17, 2021, at 15:27:06

In reply to Re: Help..severe anger...., posted by undopaminergic on September 17, 2021, at 12:10:28

> > But: PEA administered during MAO-B inhibition in sufficient quantities yields a powerful antidepressant (or stimulant) effect.
> >
>
> Alternative theory: there could be a MAO-B substrate that is depressogenic. It may be hitherto unidentified as a MAO-B target.
>
> MPTP is a neurotoxin that produces Parkinson's disease. It is actually a precursor to the actual toxin; MAO-B converts MPTP to the MPP+ ion. There could be some other toxin that produces depression rather than Parkinson's, and which is *inactivated* by MAO-B, so that if you inhibit MAO-B, this substance is let loose on the CNS.

This is an excellent thought. However, I'll need a few more years to understand it.


:-)

- Scott



Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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poster:SLS thread:1116908
URL: http://www.dr-bob.org/babble/20210723/msgs/1116988.html