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Is anyone now taking or has taken TCAs? Results?

Posted by Mtom on September 6, 2021, at 9:50:33

In reply to Re: Which antidepressants are 'less' activating? linkadge, posted by SLS on August 27, 2021, at 23:26:46

This thread evolved to include considerable discussion on Tricyclics (TCAs) and the fact that Doctors seem to rarely consider them these days (in my experience) despite some (mostly older) data that they may be as effective, or possibly more so, than newer antidepressants. This was discussed earlier in the thread.

In medical literature, side effect burden is often cited as a reason to make other choices. As well as higher toxicity.

Many, many years ago I was prescribe Amitriptyline, I believe a low(ish) dose, for intense situational stress which was leading to panic attacks and early symtpoms of depression. My anxiety and depression did resolve fairly quickly, however that might have been due to the fact that I took other specific steps to change the stressful circumstances. Or, although I didn't sense this at the time, it is possible that the Amitriptyline played a role in my ability to make these changes. There is no way to know for certain.

I discontinued the Amitriptyline after about 7 to 8 months.

The adverse effects I remember were initial occasional bouts of dizziness or light-headedness accompanied by a kind of brain fog feeling which resolved over a relatively short period of time. More difficult to deal with were somnolence (difficulty waking up in the morning) and fairly significant weight gain.

Is anyone currently taking a Tricyclic or has taken one in past? What were your specific experiences regarding efficacy and adverse effects?

Thank you!




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