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Re: Can mirtazapine (Remeron) cause increased anxiety? undopaminergic

Posted by SLS on August 26, 2021, at 19:37:42

In reply to Re: Can mirtazapine (Remeron) cause increased anxiety? SLS, posted by undopaminergic on August 26, 2021, at 12:28:48

UD:

> Many of the dirty ones, ie. those groping on a plethora of receptors. For example clozapine, quetiapine, and especially asenapine. Now that I checked it out, though, they (except asenapine) seem to have lower affinity for alpha2A than -2B and -2C. It is my understanding that guanfacine is primarily an alpha2A agonist, and that this is the receptor important for working memory.


I like asenapine (Saphris). I tried it and it had an unambiguous antidepressant affect. It lasted several weeks - which for me, was impressive. A friend of mine who has schizoaffective disorder (bipolar type), found asenapine to produce a stable antidepressant response with a more or less global improvement, including cognition and memory.

Do you have any ideas as to why asenapine would produce such robust cognitive and memory improvements?

Do not pass up asenapine unless you have reason to believe that it would be unsafe. I don't know why asenapine has been so neglected.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

The only thing necessary for the triumph of evil is that good men do nothing.

 

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