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Re: Abilify for Erectile Dysfunction? undopaminergic

Posted by Jay2112 on August 21, 2021, at 11:17:24

In reply to Re: Abilify for Erectile Dysfunction?, posted by undopaminergic on August 21, 2021, at 2:26:55

> >
> With bromocriptine, an ergoline-based drug, you should watch out for heart valvulopathy and fibrosis. Why not use pramipexole (Sifrol, Mirapex) or ropinirole (Requip)?

Well, I have tried both Requip and Mirapex. They just didn't do anything for my ED. The bromocriptine is actually starting to help. I honestly think, as with most drugs, it has to do with genetic enzymes, and the processing in the body.
> > A couple of questions...1) Would higher dose Abilify work better for ED? (i.e. 30mg?)
> >
> Absolutely not. Abilify is an agonist-antagonist, a dopamine partial agonist, and at low doses, it stimulates dopamine receptors but in higher doses, the net effect is to antagonise them -- that is why Abilify is used for schizophrenia and other psychoses. So more is not merrier with Abilify.
>> I wonder why you'd need Abilify as a dopamine *agonist* when you are already taking one in the form of bromocriptine?

There are a few reasons I am going this route. 1) I do need an antipsychotic, as I am bipolar II, and have had some psychotic episodes. All other antipsychotics just make me feel so tired, majorly apathetic, and at times, suicidal. I really am a vegetable on these, and Abilify completely changed that, and it seems my lithium greatly prevents the irritation of dopamine agonism with Abilify. 2) Suprisingly, the bromo feels very smooth, to me.

> > 3) What would be the best SRI to augment with for a bit more antidepressant qualities, while the bromo and Abilify address the ED problem? I am thinking low dose Prozac or Zoloft.
> >
> SRIs have sexual side effects. I think it is called anorgasmia. I think Prozac is less liable to this effect than Zoloft.

Well, I just think I will stick with my Effexor for now. It is pretty much like an SRI.

I may also consider trying/adding the Mirapex in this combo. I have type II diabetes, which also contributes to the ED. But, I am on the right road.
> -undopaminergic
Thanks so kindly...

Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-




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