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Re: Low dose venlafaxine basically an SSRI? linkadge

Posted by NKP on August 9, 2021, at 10:18:48

In reply to Re: Low dose venlafaxine basically an SSRI?, posted by linkadge on August 9, 2021, at 6:54:25

> On paper, effexor can become dopaminergic in VERY high does. However, in vivo, there is no evidence that effexor actually occupies the dopamine transporter in the human brain (even at the top of the dose range). The psychotic reaction you mentioned was only hypothesized to be related to dopamine, there was no objective evidence of this.
>
> There have been studies showing that effexor can affect norepinephrine even in lower doses (75mg) and this effect is dose dependent. Yes, it primarily affects serotonin, but there will still be some noradrenergic action. This becomes more pronounced in higher doses.
>
> So, yes increasing the dose could very well lead to additional therapeutic effect.
>
> Linkadge

Thank you for this information.

Everywhere I look, I see people badmouthing venlafaxine, saying it's basically an SSRI with the side-effects of an SNRI, hence why I was wondering. But I will trust my doctor and stick to the treatment.


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URL: http://www.dr-bob.org/babble/20210723/msgs/1116324.html