Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: GABAergic hypofunction in psychosis?

Posted by undopaminergic on August 3, 2021, at 12:01:57

In reply to Re: GABAergic hypofunction in psychosis?, posted by linkadge on August 3, 2021, at 6:27:26

> Cognition in schizophrenia is usually more impaired (on an ongoing basis) whereas in bipolar impairment usually more state dependent.

That rhymes with my experience. The cognitive impairment began as part of my burnout syndrome and it only went away during my first manic episode. It is interesting to note that the only thing that went wrong with this first and most intense manic episode is that it came to an end and I went back into my usual depressive state. For that reason, you may consider it "hypo"-mania, but it was a full blown mania in terms of intensity. I've had other, less intense episodes, but they did not feature a resolution of the cognitive impairment, and they ended in the hospital.

> Although, cognitive issues in bipolar can accumulate over time if symptoms do not remit.

I do not really feel they have accumulated, except insofar as taking anticholinergics and the natural consequences of aging probably play more of a role than I easily notice. I find that my short term memory is pretty good, but working memory and long term memory are not.

> I think (don't quote me) that substance abuse history is more common in bipolar. Substance use can muddle the diagnosis however, depending on the proximity between last drug use and diagnosis.

Substance abuse (psychostimulants) probably played a greater role than I'd like to admit in my first episode of psychosis. I like to attribute it to the consequences of accumulating sleep deficit, but this was in turn largely secondary to the use of (cocaine-like ie. reuptake inhibitor) stimulants. The first episode featured auditory hallucinations, the further episodes have not so far.





Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:undopaminergic thread:1116100