Psycho-Babble Medication | about biological treatments | Framed
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Re: GABAergic hypofunction in psychosis?

Posted by undopaminergic on August 2, 2021, at 9:51:46

In reply to Re: GABAergic hypofunction in psychosis? Lamdage22, posted by linkadge on August 2, 2021, at 9:27:28

> They are also finding that many of the lines between various mental illnesses are blurred. For example, there is a high degree of overlap between the genes that influence bipolar and schizophrenia. This is no surprise given the overlap in efficacy in treatments with these two disorders.

I'm accused of having schizophrenia. Funny that I'm not accused of having bipolar, even though there is more evidence for the latter. The former is harder to diagnose with certainty; eg. you need to know how long a psychotic episode has lasted, and you have to find delusions and differentiate them from other theories and beliefs. However, the fact that negative symptoms are a factor does make it easier to diagnose someone with depression as schizophrenic. With bipolar disorder, just one episode of (hypo)mania is enough for diagnosis, although I do not necessarily agree it should be.

> You see the genetic argument as a negative. You see that suggestion that you might have a few bad genes as a negative. I see this as very liberating. The idea that one day I might be able to analyze me genes to guide treatment, or that they might be able to develop more specific targets, or gene therapy etc. as extremely liberating.

I see both perspectives. For the time being, having the wrong genes is a difficult thing to do anything about, but it won't be all that long before it's easier to address the genetic component than the environmental.





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