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Re: GABAergic hypofunction in psychosis?

Posted by linkadge on July 27, 2021, at 10:00:33

In reply to Re: GABAergic hypofunction in psychosis?, posted by Lamdage22 on July 27, 2021, at 8:20:45

The GABA deficits (that I have read of) involve reductions in an enzyme called GAD67. GAD67 is involved in the synthesis of GABA. GAD67 is reduced in the prefrontal cortex of people with schizophrenia. The reduction in GAD67 has something to do with gene methylation.





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