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Re: GABAergic hypofunction in psychosis?

Posted by undopaminergic on July 27, 2021, at 7:48:31

In reply to GABAergic hypofunction in psychosis?, posted by Lamdage22 on July 26, 2021, at 21:19:05

> Does increasing GABAergic neurotransmission lessen psychotic symptoms?

Not that I know of, but I am sure it can help indirectly, such as by calming anxiety triggered by paranoid delusions. Dopamine is mainly an inhibitory neurotransmitter, too, like GABA. Meanwhile, the glutamate theory of schizophrenia suggests that the stimulatory neurotransmitter glutamate is abnormally low at NMDA-subtype receptors.





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