Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: luvox vs other SSRI's

Posted by undopaminergic on July 24, 2021, at 12:35:23

In reply to Re: luvox vs other SSRI's, posted by linkadge on July 24, 2021, at 11:45:41

> As mentioned, luvox is a sigma-1 agonist. This activity has antidepressant / anti-OCD effects in its own right. MG per MG, escitalopram would be much more potent on the serotonin reuptake system than luvox.

Per unit (mg) of weight is not the only way to look at potency. The dose-response curve is probably more relevant than affinity. I don't have any data on how the different SSRIs compare in this regard, but I know paroxetine is considered the most potent, followed by sertraline. What I mean, is that it is possible to reach near 100% serotonin transporter inhibition with these drugs (without the need for megadoses), whereas this is not possible with drugs that have a flattening dose-response curve.





Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:undopaminergic thread:1116070