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Re: Nortriptyline Increases Dopamine.... linkadge

Posted by jay2112 on July 9, 2021, at 18:58:20

In reply to Re: Nortriptyline Increases Dopamine...., posted by linkadge on July 8, 2021, at 18:22:41

> Yes, and norepinephrine reuptake inhibitors also increase dopamine in the hippocampus. Some of the other actions of nortriptyline (5-ht2 antagonism, and muscarinic antagonism) will also increase dopamine.
>
> Linkadge

I find it fascinating, all of the use of 5-htp antagonism, and inverse agonists, treating multiple disorders. I have a very good response to 5-ht2a and 5-ht2c subreceptor antagonists. Those same chemicals are used for disorders right across the psychiatric spectrum...MDD, bipolar, schizophrenia, AD(H)D, etc. Leading me to believe that the pharma industry SHOULD be making drugs that are true selective serotonin combination agonists/antagonists/inverse agonists. And take away the dopamine antagonists. (For use in non-psychotic Dx's)

Anyhow...I am rambling on. Lol. Your thoughts?

Jay


Humans punish themselves endlessly
for not being what they believe they should be.
-Don Miguel Ruiz-


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