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Re: Do you agree with NMDA hypofunction hypothesis?

Posted by linkadge on May 31, 2021, at 13:19:20

In reply to Re: Do you agree with NMDA hypofunction hypothesis?, posted by undopaminergic on May 31, 2021, at 9:53:57

It can work both ways too. Dopamine agonists often decrease NMDA function.

Schizophrenia is not a single disorder. The NMDA model seems to closer match the 'disorganized' subtype of the disorder. Whereas, the dopaminergic model seems to match the paranoid subtype. This being said, neither of these are likely at the core of the disorder. Dysfunction in dopamine or NMDA likely result from other dysfunctions.





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