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Re: Johnson + Johnson vaccine can someone explain how

Posted by alexandra_k on May 27, 2021, at 5:37:35

In reply to Re: Johnson + Johnson vaccine can someone explain how SLS, posted by Phillipa on May 17, 2021, at 23:26:22

they think the mrna and dna (from both types of vaccine) are both broken down by the body and removed entirely. they are both only in the body temporarily.

the mrna and dna are (both ultimately) translated into antigens (proteins) which are released from the cell. the spike protein antigens are identified by the t cells and b cells (i forget the precise role of t cells). the b cells make antibodies and also the b cells make more copies of themself (colonal expansion) so that next time the body is exposed to the virus a lot of antibodies can be produced very quickly.

the capacity to produce a lot of antibodies very quickly on exposure is immunological memory. that just is immunity.


some people have immunity to adenovirus. that means that the way in which the J&J vaccine works (by using adenovirus to help it get into the cell) isn't as effective for some people. some people's body destroys the vaccine before it can do it's work inside the cell. they think that increased immunity to adenovirus is one mechanism resulting in less efficacy for traditional vaccines that use adenovirus as a vector to get inside the cell.


they are starting to look, now, at how the bodies immune response is more complicated than we thought...

think about banana. how it tastes. then think about 'nature identical' banana flavoring produced in a laboratory. natural biological molecules are very large and very complicated and there are many different 'active' regions, if you like. synthetics just pick out one or two active regions that they think are responsible for most of the effect and they amplify or copy those.

they think that the bodies natural immune response to Covid is actually quite complicated. with antibodies grabbing onto different regions of the spike protein etc. our immunisations aren't as sophisticated or complex. the particular part of the spike protein that they code for...




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