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Re: Can Tryptophan or 5-HTP be used with Antidepressan

Posted by linkadge on March 15, 2021, at 16:12:56

In reply to Re: Can Tryptophan or 5-HTP be used with Antidepressan, posted by Lamdage22 on March 15, 2021, at 11:40:52

Serotonin syndrome can start quickly, in the case of 2 serotonergic drugs being combined. However, it has also been known to develop more slowly. Tryptophan has been used in conjunction with other serotonergic meds (i.e. the Dalhousie serotonin cocktail - tryptophan + lithium + clomipramine) for treatment resistant depression. However, it should be done cautiously. What causes serotonin syndrome can vary widely from person to person (possibly due to differences in sensitivity to serotonin). I often combine small amounts of tryptophan (i.e. 50mg) with effexor and lithium without any problems. I dissolve it in water and drink it slowly. You should still be cautious when taking it on a longer term basis, as serotonin can build up in the brain over time. However, it occurs along a spectrum, so if you're noticing any symptoms (i.e. especially chills), then stop everything.





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