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Re: carbamazepine (tegretol) for social anxiety

Posted by farshad on August 24, 2018, at 9:03:40

In reply to carbamazepine (tegretol) for social anxiety, posted by farshad on August 13, 2018, at 19:48:05

If anyone knows any other drugs besides carbamazepine that inhibits CRH in the hypothalamus PVN let me know.

so far I know: desipramine/imipramine,valproic acid,xanax and most Antipsychotic drugs.

from what I can tell my best choices are: valproate, carbamazepine or one of the imipramine drugs.

valproate very heavy side effects and short(ish) half life. 9-16 hours

imipramine 20 hour half life, I assume this drug has a lot of side effects and is difficult to get. It is a TCA.

that leaves carbamazepine. long half life 30 hours, not as much side effects and easy to get and does practically what imipramine does, inhibits CRH in the hypothalamus, in studies it says imipramine inhibits CRH in the PVN but for carbamazepine it only say hypothalamus but i assume it also inhibits in the PVN becuase of they are structually ssimilar drugs




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