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Re: im going to ask psydoc for doxycycline and a pro b SLS

Posted by ed_uk2010 on March 25, 2018, at 17:44:38

In reply to Re: im going to ask psydoc for doxycycline and a pro b, posted by SLS on March 25, 2018, at 17:09:02

Hi Scott,

I feel slightly irritated by the widespread beliefs which have developed in the UK about tetracyclines.

In summary, there is the impression that only doxycycline should be used for infectious disease. Minocycline has recently become frowned upon. And oxytetracycline is just used for acne.

Personally, I think the situation RE doxycycline vs minocycline is more complex.

I don't agree with the popular idea that doxycycline is universally safer than mino. A lot of people appear to find doxy much more nauseating than mino, which can interfere with treatment. Photosensitisation is also a particular problem with doxycycline. On the other hand, mino can cause dizziness, hyperpigmentation and a few rare side effects too. I really think it's better that both options are available and considered.

For CNS infection, minocycline's excellent penetration into the CNS at standard doses avoids the need to use high and nauseating doses of doxycycline (eg. 200mg twice a day).

 

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