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Re: Anyone's taking Agomelatine (Valdoxan)? Hana

Posted by SLS on September 18, 2016, at 15:18:43

In reply to Re: Anyone's taking Agomelatine (Valdoxan)? SLS, posted by Hana on September 18, 2016, at 12:30:20

> > > Looks like Valdoxan is a mild drug. I'll look into something else. Btw that new treatment looks great. Is it availbale now or not yet?

> > I have a severe anergic bipolar depression with anhedonia and cognitive impairments. I take a combination of antidepressants, mood stabilizers, and an antipsychotic with antidepressant properties. I tried switching from Abilify to Vraylar. It made me feel much worse. I am currently switching to Reluxti. So far, I am feeling better than I was on Abilify. I am very much encouraged that I will continue to improve.
> >
> > Currently:
> >
> > Parnate 80 mg/day
> > nortriptyline 150 mg/day
> > Lamictal 300 mg/day
> > lithium 300 mg/day
> > Reluxti 1.0 mg/day
> > prazosin 30 mg/day

> Sounds great! gonna suggest Reluxti to my pdoc. How long have you been on it? Are there any SEs especially in regards to sex drive?

I have been taking Reluxti for about two weeks. I noticed a positive response by day 7 at a dosage of 1.0 mg/day. In my experience, when trying an atypical AP to treat depression, I feel an improvement within a week, provided the dosage is high enough. With Reluxti, you start at 0.5 mg/day for 7 days, then 1.0 mg/day thereafter. I haven't been able to evaluate Reluxti for sexual side effects, as I take prazosin, which can reduce libido drastically. I will have to let you know about weight gain in the coming weeks. I still take 7.5 of Abilify, which I am still tapering. Reluxti is supposed to be more tolerable than Abilify if akathisia is an issue. I felt a little "drugged" for the first few days, but this sedation-like feeling disappeared completely. I will know more about the trajectory of my response to Reluxti over the next few weeks. I hope it doesn't plateau. It will be very demoralizing if I get "stuck" again.

I wish you the best.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1092111
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