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Re: ssris and sexual disfunction Lamdage22

Posted by SLS on September 16, 2015, at 15:01:47

In reply to Re: ssris and sexual disfunction, posted by Lamdage22 on September 16, 2015, at 12:46:39

> Not Brintellix?

You are right.

It gets complicated. Brintellix is not generally considered to be "selective", and I have not yet seen it listed as a SSRI. Brintellix does have the reputation of being less liable to produce sexual side effects than the SSRIs. However, it is difficult to categorize drugs when they have so many different actions.

1. Inhibitor of serotonin (5-HT) reuptake transporter
2. Agonist at 5-HT1A receptors
3. Partial agonist at 5-HT1B receptors
4. Antagonist at 5-HT3 receptors
5. Antagonist at 5-HT1D receptors
6. Antagonist at 5-HT7 receptors

Maybe there are more. I don't know. It is hard to guess which properties are the most important.

It may be that the properties of Brintellix as a ligand (substance that binds) to 5-HT receptors helps to reverse any sexual impairments brought about by its serotonin reuptake inhibition properties.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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