Psycho-Babble Medication | about biological treatments | Framed
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Re: nicotine as a medication

Posted by SLS on July 7, 2015, at 22:21:56

In reply to nicotine as a medication, posted by rjlockhart37 on July 7, 2015, at 21:57:44

Linkadge has long postulated a role for nicotine or nicotinic receptors in the treatment of depression. It turns out that a metabolite of ketamine, hydroxynorketamine (HNK), targets the alpha-7 nicotinic receptor subtype without affecting NMDA receptors. It has already demonstrated antidepressant properties preclinically. I don't know if there are plans for clinical trials, though. I imagine the drug could be patented. I am now wondering if the clinical benefit produced by ketamine for depression has little to do with NMDA receptors.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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