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Re: Medications that don't touch the 5HT1 receptor?

Posted by SLS on June 13, 2015, at 6:03:46

In reply to Re: Medications that don't touch the 5HT1 receptor?, posted by tiopenster on June 13, 2015, at 0:31:54

Thanks for the tip!

> Yes, we have very similar responses. I'm sorry to hear that. It's maddening. I have one way that boosts serotonin, norepinephrine and dopamine without the tachyphylaxis. Pardon me if you've already heard of it.
> Have you been tested to find out if you have the MTHFR genetic polymorphism? I have two parts of the gene that are affected. When I started the treatment, my depression disappeared in 2 days. Simply google bipolar and MTHFR. There are a tone of resources out there that explains the connection. The treatment is methylfolate and methyl B12. Takes a couple weeks to find the right dose, but it seems to lift all the neurotransmitters for me without the tachyphylaxis. I wonder if it would be helpful for you.
> Here's just one of a ton of articles
> Deplin is the prescription strength dose of methylfolate, but I wouldn't recommend starting with that. You can get lower doses over the counter. No one I talk to in real life knows about this, but it may be different on this board.

I tried Deplin twice in combination: once with Nardil, and once with Parate. I felt an immediate boost in mood and energy with Nardil, but not so much with Parnate. I eventually discontinued Deplin because it actually began to make my depression worse. I recovered immediately upon stopping it. Deplin made me feel worse when I tried it again recently.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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