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Re: Medications that don't touch the 5HT1 receptor? tiopenster

Posted by SLS on June 2, 2015, at 6:26:15

In reply to Medications that don't touch the 5HT1 receptor?, posted by tiopenster on May 30, 2015, at 21:58:09

Hi.

A few quick thoughts...

You pose a challenging question.

How did you come to the conclusion that 5-HT1a stimulation is bad for you?

Perhaps a partial agonist would be helpful. Brintellix is a potent serotonin reuptake inhibitor along with its antagonist effects at 5-HT7 and nearly full agonism at 5-HT1a. Abilify is more of a partial agonist at 5-HT1a receptors.

A few antidepressive agents that I think are devoid of direct serotonin effects:

bupropion
desipramine
nortriptyline
reboxetine
agomelatine
modafinil
atomoxetine
maprotiline
memantine
lamotrigine

Mirtazapine and mianserin should not affect serotonin 5-HT1a receptors.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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