Posted by Bill82 on February 12, 2015, at 16:34:43
In reply to Re: What is OCD? For those that don't know...., posted by Bill82 on February 12, 2015, at 16:29:24
Also of note, alchohal dose dependently abolishes both my compulsions and obbsessions. But as my dad was an alchoholic and I often drink way too much I refrain from drinking at all times unless I am literally going nuts(last drink was over a month ago). Alchohal also has a rebound effect in worsening my ocd gravely the next day. Alchohal to my understanding inhibits glutamate and encourages GABA in some way giving it's depressive effects. It also effects dopamine and other receptors, but it's depressive effects are primarily due to Glutamte and GABA. When on benzos I experience the same uncanny urge to take "just one more" until the bottle is gone and I wake up the next day with extreme ocd and withdrawls. However unlike alchohal when in benzos my ocd is unchanged. This has lead me to wonder about glutamate involvement, and is why I have proposed trailing some glutamatergic agents. I could be wrong but I don't see the disadvantage to this. I also beleive minocycline may have slightly helped calm some ocd, but this is most likely placebo.
poster:Bill82
thread:1075804
URL: http://www.dr-bob.org/babble/20150129/msgs/1076327.html