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Re: OCD Dont know where to go

Posted by ed_uk2010 on January 31, 2015, at 12:22:49

In reply to OCD Dont know where to go, posted by Bill82 on January 30, 2015, at 20:56:23

Hi Bill,

It all sounds like a nightmare. I do have a few suggestions which you might potentially be interested in.

Possible options:

N-acetylcysteine capsules.

N-acetylcysteine has mainly been used as a add on to SSRIs, but may be effective alone.

Small trial (in treatment refractory pts) but.... "Of the patients in the N-acetylcysteine group, 52.6% were full responders at the end of the study, which was significantly higher than 15% of the patients in the placebo group."

N-acetylcysteine is of potential benefit in various forms of impulsive behavior.... OCD, skin picking, hair pulling, pathological gambling etc.

Pregabalin capsules.

Pregabalin has been used for various anxiety disorders, mainly GAD, for which is it approved in some countries. Very small studies suggest that it may be useful in OCD. (If stopping, pregabalin must be tapered slowly to prevent withdrawal symptoms).

Saffron. Saffron has been effective in animal models of OCD, but has not been studied for this purpose in humans. Several trials have demonstrated saffron to be effective against depression in humans, at a dose of 15mg of extract, twice a day. Perhaps you could try a similar dose for your OCD? Saffron has been shown to improve sexual function in some studies.




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