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Re: i'm scared to try minocycline again, because Jeroen

Posted by SLS on August 31, 2014, at 10:38:58

In reply to i'm scared to try minocycline again, because, posted by Jeroen on August 31, 2014, at 10:19:14

> of ativan i took with it causing a seizure
>
> i don't know why it causes this with the interaction, i need to tell my doctor that i'm concerned about trying this again, but hey it works very good : S

If you do decide to take minocycline, you might consider taking vitamin C along with it. The recommended dosage is 500 mg twice a day. Studies indicate that vitamin C helps prevent the formation of hyperpigmentation. As a side effect of minocycline, dark hyperpigmentation can occur at any time during treatment - even years after its initial application. Discoloration usually appear around the teeth and gums of the mouth and on the lower legs. Hyperpigmentation is not at all dangerous. It is only of cosmetic concern.

http://www.rheumatic.org/faq.htm

" 5. WHAT IS HYPERPIGMENTATION? Minocycline can cause discoloration of the skin anywhere on the body. This is called hyperpigmentation. Large daily doses of ascorbic acid (vitamin C) may prevent this phenomenon. (Bowles WH, Baylor College of Dentistry, Texas A&M University System Protection against minocycline pigment formation by ascorbic acid, J Esthet Dent, 10(4):182-6 1998)

Dr. A. Robert Franco, a rheumatologist practicing in Riverside, California, says that hyperpigmentation occurs in about 10% to 20% of patients taking minocycline (Minocin) on a daily basis and over one year. Occasionally it may appear earlier. It occurs less frequently with patients taking Minocin on a three times per week basis. It may be necessary to switch to another antibiotic. It is usually reversible after discontinuation of the medication, but fades slowly and sometimes not completely."


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