Psycho-Babble Medication | about biological treatments | Framed
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Re: Belviq: be careful

Posted by jrbecker76 on May 28, 2014, at 21:02:40

In reply to Belviq: Finally an appropriate anorexiant? Maybe., posted by LouisianaSportsman on April 17, 2014, at 2:38:05

> Anorexiants cause side effects that may not be good, in particular, for patients that have psychiatric conditions, including anxiety.
> Lorcaserin HCl is instead a primarily selective 5-HT2C receptor agonist and has been released since last summer (2013); sold as the medication, Belviq [Arena].
> Belviq reviews on 148 reviews with a 9.4 average score. This is blockbuster status for a medicine less than a year old to have so many positive reviews on this website in a short duration.
> The only thing I generally see mentioned to address weight is metformin, or hope that Topamax causes side effects. Is that the best some PDOCs will even offer?
> The lack of this drug's popularity on forums may be due to lack of reception among the psychiatric community due to lorcaserin's serotonergic mechanism of action that causes a side effect profile also not partiuclarly indicated for patients diagnosed with some mental health disorders.
> I think that the patient should be evaluated and prescribed first-line metformin with lorcaserin, if appropriate.
> Psychiatric patients, in particular, DESERVE and NEED a weight-loss medicine that provides RESULTS, and I think Belviq may fit the bill for many patients that take neuroleptics, antidepressants and various other types of psychiatric medications that coagulate excess adipose tissue.
> Does anyone have experience or thoughts?

Please be careful with Belviq. I would highly caution anyone from using it who suffers from issues related to mood or anxiety.

Although rates of depression, anxiety and other psychiatric issues were similar amongst placebo and active drug in the Belviq clinical trials, a significant number of subjects dropped out of the trial due to these issues in comparison to placebo.

5-HT2c agonism has been known to cause issues with mood and anxiety. This has been demonstrated mostly through studies with m-CPP, a drug similar to Belviq (Lorcaserin).

By contrast, 5-HT2c antagonism has well-known anxiolytic and antidepressant properties.




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