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Re: Viibryd or Brintellix= SSRI + Buspar? mogger

Posted by phidippus on January 27, 2014, at 20:45:54

In reply to Viibryd or Brintellix= SSRI + Buspar?, posted by mogger on January 27, 2014, at 16:23:28

I responded strongly to Viibryd. Buspar is 5ht1a agonist-agonizing this receptor provides both an anxiolytic and antidepressant effect. Viibryd is a partial 5ht1a agonist and Brintellix is a 5ht1a full agonist. Brintellix is also a 5-HT1B receptor partial agonist, a 5-HT1D receptor antagonist, 5-HT3A receptor antagonist, and a 5-HT7 receptor antagonist-all of which contributes to its antidepressant and anxiolytic effects.

Latuda, Geodon and Abilify are also 5ht1a agonists. In OCD, there is often too much dopamine in certain parts of the brain, so the tactic of adding an atypical antipsychotic is used. Adding an atypical with 5ht1a agonism sometimes proves particularly effective in treating OCD.





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