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Re: Prozac Derealization But Improved OCD exisessentialist

Posted by doxogenic boy on October 29, 2013, at 19:09:17

In reply to Re: Prozac Derealization But Improved OCD doxogenic boy, posted by exisessentialist on October 29, 2013, at 18:28:45

> I was only one quetiapine for six or seven weeks. It was intended to alleviate insomnia and OCD but contributed to rhinosinusitis, with which I already have great difficulty.

I don't know if you could have a bad quetiapine withdrawal after only six or seven weeks on a low dose. I have found information which go in both directions.

Fluoxetine can induce depersonalization syndrome:

http://www.ncbi.nlm.nih.gov/pubmed/1961868
(no abstract available)
Quote:
Psychosomatics. 1991 Fall;32(4):468-9.
Depersonalization syndrome induced by fluoxetine.
Black DW, Wojcieszek J.
End quote.

But fluoxetine has also been used as a treatment in depersonalization disorder (not successfully):

http://bjp.rcpsych.org/content/185/1/31.long
Excerpt:
CLINICAL IMPLICATIONS

Fluoxetine is not efficacious in treating primary depersonalisation.

The widespread use of serotonin reuptake inhibitors to treat depersonalisation in clinical practice appears unfounded.

The unresponsiveness of depersonalisation to fluoxetine supports the concept that depersonalisation disorder is a dissociative rather than a depression/anxiety spectrum disorder
End quote.

And quetiapine can cause depersonalization too:

http://www.unboundmedicine.com/medline/citation/11565631/A_case_of_depersonalization_derealization_syndrome_during_treatment_with_quetiapine_

From the link above:

A case of depersonalization-derealization syndrome during treatment with quetiapine.

Abstract

A case who schizophrenia developed patient male of a 65-year-old is reported depersonalization-derealization syndrome following treatment with quetiapine, an atypical antipsychotic. The literature is reviewed for possible biological mechanisms that may account for this phenomenon.
End quote.

- doxogenic


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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URL: http://www.dr-bob.org/babble/20131025/msgs/1053348.html