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Lou's warning-cns depression ed_uk2010

Posted by Lou Pilder on May 30, 2013, at 20:13:35

In reply to An inappropriate analogy Lou Pilder, posted by ed_uk2010 on May 30, 2013, at 17:38:13

> >On the contrary. People die from taking two drugs that can depress the CNS.
>
> We are not talking generally, we are talking specifically about the venlafaxine + oxcarbazepine combination.
>
> >A few months ago, a girl died here . She took a pain pill and later before bed she had a mixed drink.
>
> We are not discussing pain pills or alcohol. These drugs have a different mechanism of action and can both cause respiratory depression in overdose.
>
> >The drug Effexor is listed as having the effects exponentially magnified when another drug such as Trileptal is taken together.
>
> The only drugs which exponentially magnify the effects of venlafaxine are the MAOIs, and as such this combination results in toxicity. The effects of venlafaxine are not exponentially magnified by oxcarbazepine.
>

Friends,
When two drugs that have effects of sedation and such that show a depression of the cns are taken together, there is the potential of a fatal reaction due to depression of the central nervous system.
Here is a link warning those that take the ant-seizure drug Lamictal with Effexor.
Now there is a reason that the site lists this warning to those that take the two drugs together. This same warning is given to those that take Trileptal together with Effexor.
Lou
http://www.drugs.com/interactions/effexor-xr-with-lamictal-2296-1523-1430-848.html

 

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poster:Lou Pilder thread:1044214
URL: http://www.dr-bob.org/babble/20130527/msgs/1044540.html