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Re: To MAOI or not to MAOI vanvog

Posted by Tomatheus on April 1, 2013, at 19:00:58

In reply to Re: To MAOI or not to MAOI, posted by vanvog on April 1, 2013, at 18:19:02

> Amitriptyline blocks and prevents the reuptake of norepinephrine not serotonin.

According to this source (http://www.druglib.com/activeingredient/amitriptyline/), it inhibits the reuptake of both serotonin and norepinephrine. Wikipedia says the same.

I know that the Gillman article that you posted says that imipramine and clomipramine are the only tricyclics that can trigger serotonin syndrome when combined with an MAOI. Maybe the sources referenced in the article might have some information to refute the notion that amitriptyline inhibits the reuptake of both norepinephrine and serotonin, but the sources that I've come across do suggest that amitriptyline blocks serotonin transporters.

Tomatheus


Dx: schizoaffective disorder

Treatments: Abilify & Korean ginseng

tomatheus.blogspot.com


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URL: http://www.dr-bob.org/babble/20130322/msgs/1041505.html