Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Parnate Therapeutic Effect and MAOI Inhibition vanvog

Posted by cassandracomplex on March 25, 2013, at 12:32:31

In reply to Re: Parnate Therapeutic Effect and MAOI Inhibition, posted by vanvog on March 24, 2013, at 13:53:35

> "The full therapeutic dose of tranylcypromine is no less than 0.8mg/kg/day, and can be 1.5-2mg/kg/day. The 60mg/day maximum dose is a fiction. It's really around 120-200mg/day, and any competent psychiatrist knows this."
> by Chairman_MAO, I wanted to provide this quote initially but totally forgot about it.

Really? Because I see a MAOI expert (one of the founders of "atypical depression," has done numerous research studies - recently, one on Parnate + Dexedrine and now one on Parnate for bipolar) and I was pretty sure he said 60 mg to 120 mg was typical therapeutic use.

Has anyone here exceeded 120 mg? What was different about its side effect profile, if anything?

(Of course, there will always be fast metabolizers who need higher doses of meds in general but I've never known anyone who exceeded 120 mg of Parnate. If there was a partial response to 120 mg and side effects were tolerable, I can imagine that stimulant augmentation would be the next step rather than continuing to push the dose. I will be sure to ask him when I see him this week.)

Also, I wasn't aware that Parnate had a linear "mg by kg" response. When I weighed 100 lbs, I took 120 mg and now, at 115 lbs, I've been titrating onto it again and the therapeutic response has just kicked in at 70 mg. I have friends who weigh more than this who responded to lower doses (though none below 60 mg/day) but none exceeding 120/day, either.




Post a new follow-up

Your message only Include above post

Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.


Start a new thread

Google www
Search options and examples
[amazon] for

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:cassandracomplex thread:1040654