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Re: http://web.mit.edu/newsoffice/2012/better-antidepr joe schmoe

Posted by CamW on March 4, 2013, at 18:47:40

In reply to Re: http://web.mit.edu/newsoffice/2012/better-antidepr, posted by joe schmoe on March 4, 2013, at 17:15:34

> I thought that the explanation for the delayed effect was that AD's cause neurogenesis, and it takes several weeks for the new neurons to grow?

joe - I don't think that the delay is in neurogenesis, but in down-regulation (getting rid of) post-synaptic serotonergic receptors (hence the increased anxiety & other start-up side effects) and forcing the body to make more serotonin, rather than reusing the serotonin it normally recycles.

I think that this is what is going on (partially) - Cam


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poster:CamW thread:1039509
URL: http://www.dr-bob.org/babble/20130222/msgs/1039590.html