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Re: is lithium a dopamine antiagonist phillipa

Posted by SLS on October 2, 2012, at 13:38:04

In reply to Re: is lithium a dopamine antiagonist SLS, posted by phillipa on October 2, 2012, at 10:21:31

> I don't understand if nardil is used for anxiety & depression why would it cause a mania? I know it takes a good two weeks to kick in for mania. Since it's also available in a different form couldn't one take it as isn't it oratate to protect ones brain without taking the prescription lithium? Phillipa

Nardil is effective in treating both depression and anxiety, as are some of the SSRIs and SNRIs.

There is virtually no standard antidepressant that does not have the ability to induce mania in susceptible individuals. Usually, it occurs as a paroxysmal "switch". However, it is not always an immediate reaction. It can be latent in its onset and gradual in its emergence.

For me, lithium at dosages of 1200 - 1500 mg/day is pretty much worthless as a treatment for mania. Lamictal 300 mg/day is ineffective as a prophylactic against Nardil-induced mania. I find that Depakote and Zyprexa are much better for me. However, my type of bipolar disorder is atypical. Lithium monotherapy seems to work best for bipolar I disorder.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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