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Re: Latuda for depression??? SLS

Posted by phidippus on August 31, 2012, at 15:31:20

In reply to Re: Latuda for depression???, posted by SLS on August 31, 2012, at 0:40:12

"The 5-HT7 receptor is involved in thermoregulation, circadian rhythm, learning and memory, and sleep. It is also speculated that this receptor may be involved in mood regulation, suggesting that it may be a useful target in the treatment of depression."

That's what I get from Wikipedia

5ht7 vaguely said to modulate striatal and cortical dopamine function, but nobody really knows how this is any different from the modulation that occurs when you block 5ht2. Lattuda does cause significant sedation, whichits speculatedmay be a result of its effects on the 5-HT7 receptor.

http://jpet.aspetjournals.org/content/297/1/395.full.pdf


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URL: http://www.dr-bob.org/babble/20120830/msgs/1024559.html