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Re: Adding Parnate and prazosin + Topamax creepy

Posted by SLS on June 25, 2012, at 16:44:53

In reply to Re: Adding Parnate and prazosin + Topamax, posted by creepy on June 25, 2012, at 8:30:37

Hi Creepy.

> I rapid cycled on 50mg topamax.. might be a little rough titrating up to 100.

Were you steadily depressed prior to beginning Topamax?

> I was a hyper-responder when I took it though. at 50mg I had some really intense side effects most dont get until higher doses. Maybe something else I was taking at the time raised my levels? Dunno.

What sorts of effects did you experience?

> Its supposedly good at taming angry outbursts in PTSD.

I didn't know that. I have seen it do this for bipolar disorder, mixed-state.

> But whether thats due to calming a mixed state or something else like slowing the amygdala I have no idea.

That's an interesting thought.

> I get the feeling the docs dont either! =(

I know.

> Zoloft has been good on my PTSD, but my body seems to respond by 'somatizing' the depression so now I have pain and fatigue.

Experiencing the somatic symptoms of depression or drug side effects is not the same thing as "somatization".

> What symptoms make your doc think you have PTSD?

Childhood history of physical abuse and neglect.

He thinks that I might have "developmental PTSD", and that this, in part, is driving the depression and creating a biological substrate for my presentation of rapid relapse upon response to antidepressant treatment.

http://www.positivehumandevelopment.com/developmental-ptsd.html


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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poster:SLS thread:1005781
URL: http://www.dr-bob.org/babble/20120608/msgs/1020202.html