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Re: ADs may do more Harm than Good -New Research paper » SLS

Posted by zazenducke on May 4, 2012, at 10:33:22

In reply to Re: ADs may do more Harm than Good -New Research paper » zazenducke, posted by SLS on May 3, 2012, at 21:03:03

> > "Crazy Like Us" describes the campaign to teach Japan how to be depressed. And this was done without direct advertising of meds. It was public service announcments to sell the illness and then the AD sales followed.
> According to the book, when did the US begin this campaign process in Japan?

I don't have the book at hand but this from the NYTimes

In the late 1980's, Eli Lilly decided against selling Prozac in Japan after market research there revealed virtually no demand for antidepressants. Throughout the 90's, when Prozac and other selective serotonin reuptake inhibitors, or S.S.R.I.'s, were traveling the strange road from chemical compound to cultural phenomenon in the West, the drugs and the disease alike remained virtually unknown in Japan.

Then, in 1999, a Japanese company, Meiji Seika Kaisha, began selling the S.S.R.I. Depromel. Meiji was among the first users of the phrase kokoro no kaze. The next year, GlaxoSmithKline -- maker of the antidepressant Paxil -- followed Meiji into the market. Koji Nakagawa, GlaxoSmithKline's product manager for Paxil, explained: ''When other pharmaceutical companies were giving up on developing antidepressants in Japan, we went ahead for a very simple reason: the successful marketing in the United States and Europe.''

Direct-to-consumer drug advertising is illegal in Japan, so the company relied on educational campaigns targeting mild depression. As Nakagawa put it: ''People didn't know they were suffering from a disease. We felt it was important to reach out to them.'' So the company formulated a tripartite message: ''Depression is a disease that anyone can get. It can be cured by medicine. Early detection is important.''

> Japan has had antidepressants since the early 1980s, some of which we will never see. This was true before the introduction of Prozac. Rolipram and adinazolam are two examples of Japanese antidepressants that have been available since 1983.
> The French have been ahead of us in many ways in the definition and treatment of mental illness. The first antipsychotic, Thorazine, was developed in France by Rhône Poulenc in 1951. The French also have had lots of antidepressants that are exclusive to that country. The first SSRI was not Prozac. It was a drug called zimelidine. Zimelidine was developed in the late 1970s and sold in Europe until fatal side effect emerged (Guillain-Barré syndrome). I don't know in what country imipramine, the first tricyclic antidepressant, was first synthesized, but it was the Swiss who discovered its therapeutic properties.
> I would have to say that the French and Swiss were complicit with the Americans in exporting mental health.

I don't believe I ever said the Americans were exporting "mental health". I don't agree with statement.




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