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Re: methamphetamine + Parnate Shes_Initforthemoney

Posted by SLS on May 1, 2012, at 9:56:48

In reply to Re: methamphetamine + Parnate SLS, posted by Shes_Initforthemoney on May 1, 2012, at 9:27:22

> > > The amphetamines reverse the transport of serotonin norepinephrine and dopamine - effectively causing both reuptake inhibition and release.
> > >
> > > They can cause serotonin syndrome in combination with MAOIs.
> >
> > I know that methamphetamine is a potent serotonin releaser, but what about d-amphetamine?
> >
> > I have been on Parnate 120 mg and added 40 mg of Dexedrine. I was also taking desipramine at the time. I have also added Dexedrine to Nardil 90 mg while also taking nortriptyline. Maybe I just got lucky, but these combinations have been considered safe for many years.
> >
> >
> > - Scott
>
> Doesn't Parnate partially convert to amphetamine as a metabolite?
>
> Jay


This has been the subject of debate for over 40 years. Most believe that there are no amphetamine metabolites of Parnate. However, one study of a person who overdosed on Parnate showed amphetamine in their blood stream.

http://www.ncbi.nlm.nih.gov/pubmed?term=tranylcypromine%20amphetamine%20overdose


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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