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Re: Imipramine, Tryptophan, Sertraline combination.

Posted by bleauberry on April 22, 2012, at 7:52:59

In reply to Imipramine, Tryptophan, Sertraline combination., posted by Exisessentialist on April 20, 2012, at 21:00:15

My first hunch was that if serotonin syndrome was a risk in this case, then it would have already happened. That's because zoloft is at a high dose and tryptophan is at a super high dose.

One thing for sure....your depression is not much related to serotonin. The inability of zoloft (serotonin) and tryptophan (serotonin) to make a big impact proves it. With that viewpoint, then a TCA makes very good sense. I like SLS suggestion of nortriptyline. I also like the general impression that imipramine might have more depression impact potential than nortriptyline. I wouldn't at this point put too much worry into which TCA to choose, just choose one and know going into it that it might be just one of 3 you will try. At this point the best choice it seems to me would be to go with the doc's hunch.

To counterbalance all that serotonin you've got going on you could also do a ritalin trial and an adderall trial....just a few days sort of test it out and see if there is anything there for you. Unlike most other meds, these work fast good or bad.

The simple addition of rhodiola rosea is as worthy as any other choice. Its potential with your cocktail is at least as good as other med options but in my mind potential better than the meds and comes with wide spectrum stress tolerance/disease resistance mechanisms as well.




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