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Re: Adding Parnate and prazosin. g_g_g_unit

Posted by SLS on April 7, 2012, at 6:18:13

In reply to Re: Adding Parnate and prazosin. SLS, posted by g_g_g_unit on April 7, 2012, at 0:37:03

> > I can't say that prazosin helps keep me asleep. Perhaps I am not taking enough at night to see a difference. My sleep is choppy, and I wake up a several times during the night. This disturbed sleep is the result of both adding Parnate and poor sleep hygiene. I allow myself to sleep too much during the day. I often fall asleep somewhere between 7:30 PM to 9:00 PM and wake at midnight. I have trouble going back to sleep after that. I just took some Ativan so that I can get through the rest of the night. I will use a sleep aid only occasionally.
> Do you suspect that the choppy sleep will improve the longer you stay on Parnate?

Perhaps. I am not sure how things will play out at this point.

When I was younger, I experienced total sleep deprivation when Parnate was combined with desipramine, but not when taking Parnate alone. For me, insomnia has been a good prognosticator of positive response to treatment. For the entire time I was on combination treatment, I don't think that the insomnia mitigated over time. However, it would be difficult for me to know for sure because the treatment of my insomnia was so effective.

triazolam (Halcion) 1.0 mg
lorazepam (Ativan) 4.0 mg

Later in my treatment history, the Parnate + desipramine combination treatment no longer produced insomnia. It also never worked again. Now, if I am losing too much sleep, I will take a combination of zaleplon (Sonata) and lorazepam (Ativan). If initiating sleep were to be refractory to this treatment, I would have to convince my doctor to use triazolam in place of zaleplon. Doctors are squeamish about prescribing triazolam. The drug got developed a reputation for having amnestic effects. However, I think zolpidem (Ambien) is just as bad as triazolam with respect to producing amnesia.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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