Psycho-Babble Medication | about biological treatments | Framed
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Re: Can't tolerate meds,TIRED all the time, + Deplin

Posted by zatar on October 19, 2011, at 23:13:37

In reply to Re: Can't tolerate meds,TIRED all the time, + Deplin, posted by jono_in_adelaide on October 19, 2011, at 18:55:57

> You might have to try and "suck it up" a bit re side effecs, with antidepressants, you get side effects first, and benifits later..... and the side effects tend to fade with time, so you often feel worse for a couple of weeks before you feel better.
> For sleep, I'd either go back to doxepin 10mg, or try generic ambien 10mg.
> For the depression and tiredness (and FMS) desipramine, starting at 25mg per day and slowly increasing till you get releif (upto 150me per day if needed)
> If you cant tolorate desipramine in an effective doseage, then Viibryd would be well worth

I've "sucked it up" quite a bit. Prozac was the worst 2 months of my life. I give all my med trials at least 2-3 months, but because of Prozac's long half life, I had serotonin syndrome for a LONG time. We're talking about 1/8-1/4 the usual dose. I actually wake up with jaw and neck muscle fasciculations when taking SSRIs.

Haven't tried desipramine. Nortriptyline didn't do much for me.

The sleep specialist (neurologist) that I saw last week said that 3-6 mg. of doxepin is supposed to be better than even 10 mg.

Ambien and such is supposed to mess with sleep architecture. My sleep studies show that I get ZERO deep sleep. My REM sleep is OK, so I wouldn't meet the criteria for narcolepsy, which is the ONLY indication for Xyrem. The FDA did not approve Xyrem for Fibromyalgia.

Even Klonopin is supposed to mess with sleep architecture. Sleep meds I've tried keep me asleep (i.e. I don't wake up), but the quality of my sleep sucks, hence the "idiopathic daytime somnolence" (medical speak for I fell asleep every two hours during the daytime during a study).

Haven't tried Ambien, but my sleep doctor said it probably wouldn't do much for me.





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