Posted by floatingbridge on June 11, 2011, at 19:11:40
In reply to Re: my research: parnate vs nardil, posted by hyperfocus on June 11, 2011, at 18:03:43
Hey, hp, This is good stuff. Thanks
> http://www.ncbi.nlm.nih.gov/pubmed/6123888
> Administration of amitriptyline greatly diminished the pressor response to intravenous tyramine in patients receiving monoamine-oxidase inhibitors (MAOIs). Dothiepin and trimipramine, however, produced little change in
sensitivity to tyramine. It is suggested that a combination of amitriptyline and an MAOI, started together in a modest dose that is then increased, may protect patients against the potential dangers of eating tyramine-containing foods. However, because MAOIs allow a high proportion of ingested tyramine to be absorbed into the systemic circulation,
patients treated with MAOIs, even in combination with amitriptyline, should not be encouraged to eat foods containing tyramine.
>
> There are a couple of studies like this.
fb if the EMSAM causes you sleep issues then it's highly likely Parnate would too.
So I guess the best tack would be attacking the insomnia before you decide to switch MAOIs.I'm not rushing any changes. Thanks for asking. I appreciate it. If emsam can work, that's perfect. It's easy. It doesn't quite hit the depression, hence my leg work here. I'm just comparing the maoi's because I am done with snri's.
>I know I keep banging away at the same drum but there are a lot of reasons why amitrip would be a good match for you.You're a good drummer :-) Last talk with pdoc was that ami was still a possibility for me, so no worries. He's just freaked about my fatigue level and insomnia. He doesn't know what to do, and neither do I. My body rejects lots of meds.
>The biggest SE of amitriptyline is sedation, which would be beneficial to you.
It might beat the current Valium.
Thanks for all the good info. You know I'll keep you posted.
Warmly,
fb
* and whoever gazes at the stars will never again be quite alone...
c-ptsd & attendant health concerns
poster:floatingbridge
thread:987705
URL: http://www.dr-bob.org/babble/20110610/msgs/987790.html