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Re: Lithium and Lamictal Redundant in Unipolar MDD? desolationrower

Posted by SLS on May 2, 2011, at 15:16:26

In reply to Re: Lithium and Lamictal Redundant in Unipolar MDD?, posted by desolationrower on May 2, 2011, at 14:11:30

> I would guess the average study doesn't have enough statistical power to pick up the benefit of both vs just one, so even if you did find such evidence, i would tend to discount it
>
> -d/r


Still, it would be nice if those people who provide the statement that lithium and Lamictal are redundant when treating MDD provide some rationale for making it - anything. The two drugs are nothing alike. Even if they did have common biological properties, I can't imagine that anyone could prove that such different molecules can never provide therapeutic results when used in tandem. To say that two drugs are redundant is to say that one should not bother to entertain the notion that combination treatment is worth trying.

Do you think Lamictal can help in unipolar depression? If so, then I feel quite strongly that there is enough proof of concept to study the issue further. There is no doubt that lithium can help as an augmenting agent.

Without providing a reason why lithium and Lamictal are redundant, I don't think one should discourage another from trying combination therapy if nothing else has helped.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

 

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poster:SLS thread:984341
URL: http://www.dr-bob.org/babble/20110502/msgs/984369.html