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Re: clomipramine + GERD

Posted by ed_uk2010 on September 11, 2010, at 14:24:46

In reply to clomipramine + GERD, posted by g_g_g_unit on September 10, 2010, at 23:16:49

> I'm prone to gastrointestinal reflux which was relatively dormant after I instated some diet changes, but it's being totally aggravated on clomipramine (day 2 @ 25mg at night). I wake up in the morning with my oesophagus feeling charred.
> Could this side-effect be ameliorated by returning to proton-pump inhibitors?

Anticholinergics may slow gastric emptying and aggravate reflux. PPIs are normally effective for GERD, you will soon know whether or not they are going to help. Perhaps you could try omeprazole 20mg or lansoprazole 30mg.




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