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Re: Another semi failed trial morgan miller

Posted by linkadge on September 9, 2010, at 14:04:00

In reply to Re: Another semi failed trial, posted by morgan miller on September 9, 2010, at 13:47:02

Well, here's my 2 cents:

The fact that people on revolution health find abilify effective doesn't really say a whole lot about its overall effectivness as an adjunct.

With sites like this, you often have non-response bias, i.e. you are not randomly seeking the experiences of a pool of *all* abilify users. Instead you are simply relying on the responses of those who respond on the site.

Those who have a positive response to a certain medication are more likely (to have the energy and motivation) to want to share their experiences (unless somebody has a *really* negative response). As a result, the responses from boards like revolution health are likely to be more positive than what would be obtained through random sampling of all users of Abilify.

This is why time is so important to the establishment of the utility of a particular medication. Things can really look great in the short term (i.e. remember the lamictal craze of 2004? - this is in spite of the fact that on the GSK trial registry, lamictal has failed something like 10x more psychiatric trials than it has ever proven useful for - and when it has proven useful it was not on the primary outcome measures)

Linkadge


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URL: http://www.dr-bob.org/babble/20100908/msgs/961807.html