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Re: still struggling with proper antidepressant

Posted by linkadge on April 28, 2010, at 17:52:06

In reply to Re: still struggling with proper antidepressant linkadge, posted by Roslynn on April 28, 2010, at 17:04:05

>Is that for someone who is bipolar I?

>I am bipolar II, but my doctor seems to think >the APs are better in that they would address >depression better than a mood stabilizer

Nothing is true for people with bipolar II :) Some studies suggest that people do better with antidepressant monotherapy in bipolar II than with mood stabilizers or AP's.

Seroquel (and perhaps zyprexa) have the most evidence for antidepressant effects, but, most of this research is done for the augmenation of antidepressant agents.

Antipsychotics are in fashon with some doctors for BP II, but they don't really have the track record / evidence for helping depression in monotherapy. I guess if it works for you than this is all that matters. AP's have evidence for treating acute mania, but conventional thought is that they are discontinued when mania abates.

I'd prefer lithium monotherapy to an AP any day, but thats just because it feels much smoother and has less side effects.





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