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Re: Stimulants for TRD

Posted by bulldog2 on November 13, 2009, at 16:54:45

In reply to Re: Stimulants for TRD bulldog2, posted by conundrum on November 13, 2009, at 12:03:01

> When you said you feel good for a few days and then it decreases, do you mean you feel high for a few days and then normal levels of emotions?
>
> Can on still feel euphoric from normal life events once you have a bit of a tolerance or do you remain somewhat anhedonic?

Yes for the first few days you have a bit of euphoria or if one's abusing the stims a lot of euphoria which I no longer enjoy. After several days the stim effect is still there but most of the mood effect is gone. This might be helpful for add but not for depression. Might be more helpful in combination with other meds.

As I mentioned before there are meds to counter the tolerance such as memantine but I could not tolerate this med.

Actually a combinaton of opiates and stims feels better than either. They seem synergistic. The opiates take the rough edge off the stims.

I might try low dose amitriptyline with the vyvanse. I know tcas can potentiate the effects of stims. I tried 10 mg amitriptyline with vyvanse. I can't find any research that they prevent tolerance. Bit it might be worth a shot. Keep the tca dose low.

 

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URL: http://www.dr-bob.org/babble/20091107/msgs/925628.html