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Re: More likely to cause insomnia, Nardil or Parnate? morganpmiller

Posted by softheprairie on June 24, 2009, at 6:19:28

In reply to Re: More likely to cause insomnia, Nardil or Parnate?, posted by morganpmiller on June 23, 2009, at 22:16:27

I wish there was some wonder MAO I that was a sort of cross between Parnate and Nardil.

Marplan is sort of a cross between Parnate and Nardil, some say. All three of these MAOIs have insomnia as a very common side effect, though. I remember an article I've linked to in the past on these boards, but that I don't have right with me now. One of the authors is Harvard psychiatrist Jonathan Coles. Anyways, in their article it recommends adding both a sleep aid to the MAOI for the insomnia and a low dose of a stimulant for the afternoon sleepiness that often comes with the MAOIs. It specifically says that altering the time of day that the doses of the MAOI are administered does not usually resolve the insomnia.

I face in part the same dilemma you do -- having both very low energy and anxiety (in addition to depression). It seems all that I know to be helpful to anxiety make one more tired. Nardil and Parnate, at least by reputation, each help one and hurt another aspect. (Nardil helps anxiety, worsens energy, while Parnate worsens anxiety, helps energy, it seems, although I have seen multiple people say Parnate made them more tired.)
This is just from my reading a lot; the only MAOI I have been on is Emsam. I'm adequately satisfied with my desipramine and adjuncts coctail to stay put for now, but I do keep these in mind for possible future trials if things get worse for me.




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